These are a group of medicines called Platelet IIB/IIIa inhibitors and anti-thrombin drugs (Bivalirudin) which make the platelets (blood cells that help in clotting) ‘less sticky’ and reduce the chances of blood clot formation. These drugs are used during stenting, because if a blood clot forms near or about the stent, then all the effort and expense of angioplasty goes wasted.
Examples of such drugs are Abciximab (Reopro), Epifibatide (Integrilin, Eptiflo, Agramed etc). These drugs prevent blood clots near the stents. Now-a-days they are also used during Unstable Angina or during or after a Heart Attack or during Angioplasty.